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They actually happen in the brain, which is possibly one reason that medications like selective serotonin reuptake inhibitors impact orgasm for so many users. “We generally feel them in the genitals, and we’ll feel a powerful orgasm all over the body,” Queen says. “But the orgasm itself occurs in the brain.” When the millions of nerve endings in the genitals are stimulated and aroused, they send messages to the nucleus accumbens, otherwise known as the brain’s pleasure center. Serotonin is primarily found in the gastrointestinal tract (GI tract), blood platelets, and the central nervous system (CNS) of animals, including humans.
During orgasm, the brain is also flooded with oxytocin, oxytocin is normally produced by the paraventricular nucleus of the hypothalamus and released by the posterior pituitary gland. It plays a role in social bonding, sexual reproduction in both sexes.
During and after childbirth. Oxytocin is released into the bloodstream as a hormone in response to stretching of the cervix and uterus during labor and with stimulation of the nipples from breastfeeding. the chemical responsible for feelings of intimacy and connection.
Both men and women experience this hormonal surge, but higher levels of testosterone in the male brain may combat some of the effects, which may explain why many women experience more intense feelings of connection after sex than men.
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